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EXT1 antibody (AA 1-746)

This Rabbit Polyclonal antibody specifically detects EXT1 in WB and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Catalog No. ABIN515425

Quick Overview for EXT1 antibody (AA 1-746) (ABIN515425)

Target

See all EXT1 Antibodies
EXT1 (Exostosin 1 (EXT1))

Reactivity

  • 30
  • 2
  • 2
  • 1
Human

Host

  • 27
  • 5
Rabbit

Clonality

  • 27
  • 5
Polyclonal

Conjugate

  • 19
  • 6
  • 3
  • 2
  • 1
  • 1
This EXT1 antibody is un-conjugated

Application

  • 28
  • 14
  • 10
  • 7
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Binding Specificity

    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-746

    Purpose

    Rabbit polyclonal antibody raised against a full-length human EXT1 protein.

    Sequence

    MQAKKRYFIL LSAGSCLALL FYFGGLQFRA SRSHSRREEH SGRNGLHHPS PDHFWPRFPD ALRPFVPWDQ LENEDSSVHI SPRQKRDANS SIYKGKKCRM ESCFDFTLCK KNGFKVYVYP QQKGEKIAES YQNILAAIEG SRFYTSDPSQ ACLFVLSLDT LDRDQLSPQY VHNLRSKVQS LHLWNNGRNH LIFNLYSGTW PDYTEDVGFD IGQAMLAKAS ISTENFRPNF DVSIPLFSKD HPRTGGERGF LKFNTIPPLR KYMLVFKGKR YLTGIGSDTR NALYHVHNGE DVVLLTTCKH GKDWQKHKDS RCDRDNTEYE KYDYREMLHN ATFCLVPRGR RLGSFRFLEA LQAACVPVML SNGWELPFSE VINWNQAAVI GDERLLLQIP STIRSIHQDK ILALRQQTQF LWEAYFSSVE KIVLTTLEII QDRIFKHISR NSLIWNKHPG GLFVLPQYSS YLGDFPYYYA NLGLKPPSKF TAVIHAVTPL VSQSQPVLKL LVAAAKSQYC AQIIVLWNCD KPLPAKHRWP ATAVPVVVIE GESKVMSSRF LPYDNIITDA VLSLDEDTVL STTEVDFAFT VWQSFPERIV GYPARSHFWD NSKERWGYTS KWTNDYSMVL TGAAIYHKYY HYLYSHYLPA SLKNMVDQLA NCEDILMNFL VSAVTKLPPI KVTQKKQYKE TMMGQTSRAS RWADPDHFAQ RQSCMNTFAS WFGYMPLIHS QMRLDPVLFK DQVSILRKKY RDIERL

    Cross-Reactivity

    Human

    Characteristics

    Antibody reactive against mammalian transfected lysate.

    Immunogen

    EXT1 (NP_000118.2, 1 a.a. ~ 746 a.a) full-length human protein.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    In 1x PBS, pH 7.4

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Tian, Yan, Wen, Li, Li, Cai, Li, Du, Chen: "A splice mutation and mRNA decay of EXT2 provoke hereditary multiple exostoses." in: PLoS ONE, Vol. 9, Issue 4, pp. e94848, (2014) (PubMed).

  • Target

    EXT1 (Exostosin 1 (EXT1))

    Alternative Name

    EXT1

    Background

    Full Gene Name: exostosin 1
    Synonyms: EXT,LGCR,LGS,TRPS2,ttv

    Gene ID

    2131

    NCBI Accession

    NM_000127

    Pathways

    Glycosaminoglycan Metabolic Process
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