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EXT2 antibody (AA 1-718)

The Mouse Polyclonal anti-EXT2 antibody has been validated for WB. It is suitable to detect EXT2 in samples from Human. There is 1 publication available.
Catalog No. ABIN515426

Quick Overview for EXT2 antibody (AA 1-718) (ABIN515426)

Target

See all EXT2 Antibodies
EXT2 (Exostosin 2 (EXT2))

Reactivity

  • 25
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Host

  • 23
  • 1
  • 1
Mouse

Clonality

  • 24
  • 1
Polyclonal

Conjugate

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  • 2
  • 2
  • 1
  • 1
This EXT2 antibody is un-conjugated

Application

  • 18
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  • 11
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  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-718

    Purpose

    Mouse polyclonal antibody raised against a full-length human EXT2 protein.

    Sequence

    MCASVKYNIR GPALIPRMKT KHRIYYITLF SIVLLGLIAT GMFQFWPHSI ESSNDWNVEK RSIRDVPVVR LPADSPIPER GDLSCRMHTC FDVYRCGFNP KNKIKVYIYA LKKYVDDFGV SVSNTISREY NELLMAISDS DYYTDDINRA CLFVPSIDVL NQNTLRIKET AQAMAQLSRW DRGTNHLLFN MLPGGPPDYN TALDVPRDRA LLAGGGFSTW TYRQGYDVSI PVYSPLSAEV DLPEKGPGPR QYFLLSSQVG LHPEYREDLE ALQVKHGESV LVLDKCTNLS EGVLSVRKRC HKHQVFDYPQ VLQEATFCVV LRGARLGQAV LSDVLQAGCV PVVIADSYIL PFSEVLDWKR ASVVVPEEKM SDVYSILQSI PQRQIEEMQR QARWFWEAYF QSIKAIALAT LQIINDRIYP YAAISYEEWN DPPAVKWGSV SNPLFLPLIP PQSQGFTAIV LTYDRVESLF RVITEVSKVP SLSKLLVVWN NQNKNPPEDS LWPKIRVPLK VVRTAENKLS NRFFPYDEIE TEAVLAIDDD IIMLTSDELQ FGYEVWREFP DRLVGYPGRL HLWDHEMNKW KYESEWTNEV SMVLTGAAFY HKYFNYLYTY KMPGDIKNWV DAHMNCEDIA MNFLVANVTG KAVIKVTPRK KFKCPECTAI DGLSLDQTHM VERSECINKF ASVFGTMPLK VVEHRADPVL YKDDFPEKLK SFPNIGSL

    Cross-Reactivity

    Human

    Characteristics

    Antibody reactive against mammalian transfected lysate.

    Immunogen

    EXT2 (NP_000392, 1 a.a. ~ 718 a.a) full-length human protein.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    No additive

    Preservative

    Without preservative

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Farhan, Wang, Robinson, Prasad, Rupar, Siu, Hegele: "Old gene, new phenotype: mutations in heparan sulfate synthesis enzyme, EXT2 leads to seizure and developmental disorder, no exostoses." in: Journal of medical genetics, Vol. 52, Issue 10, pp. 666-75, (2015) (PubMed).

  • Target

    EXT2 (Exostosin 2 (EXT2))

    Alternative Name

    EXT2

    Background

    Full Gene Name: exostoses (multiple) 2
    Synonyms: SOTV

    Gene ID

    2132

    NCBI Accession

    NM_000401

    Pathways

    Glycosaminoglycan Metabolic Process
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