GZMM antibody (AA 85-193)

Catalog No. ABIN516325

This Mouse Monoclonal antibody specifically detects GZMM in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for GZMM antibody (AA 85-193) (ABIN516325)

Target: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4D11

Product Details anti-GZMM Antibody

Binding Specificity: AA 85-193

Purpose: Mouse monoclonal antibody raised against a partial recombinant GZMM.

Sequence: DSPGLTFHIK AAIQHPRYKP VPALENDLAL LQLDGKVKPS RTIRPLALPS KRQVVAAGTR CSMAGWGLTH QGGRLSRVLR ELDLQVLDTR MCNNSRFWNG SLSPSMVCL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GZMM (NP_005308, 85 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GZMM antibody (ABIN516325)

Schiffer, Letzian, Jost, Mladenov, Hristodorov, Huhn, Fischer, Barth, Thepen: "Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells." in: Cancer letters, Vol. 341, Issue 2, pp. 178-85, (2013) (PubMed).

Target Details for GZMM

Target: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Alternative Name: GZMM

Background: Full Gene Name: granzyme M (lymphocyte met-ase 1)
Synonyms: LMET1,MET1

Gene ID: 3004

NCBI Accession: NM_005317