LAG3 antibody (AA 1-360)

Catalog No. ABIN517422

Cited in 1 publication. The Rabbit Polyclonal anti-LAG3 antibody (ABIN517422) specifically detects LAG3 in WB. The antibody is reactive with Human samples.

Quick Overview for LAG3 antibody (AA 1-360) (ABIN517422)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LAG3 Antibody

Binding Specificity: AA 1-360

Purpose: Rabbit polyclonal antibody raised against a full-length human LAG3 protein.

Sequence: MWEAQFLGLL FLQPLWVAPV KPLQPGAEVP VVWAQEGAPA QLPCSPTIPL QDLSLLRRAG VTWQHQPDSG PPAAAPGHPL APGPHPAAPS SWGPRPRRYT VLSVGPGGLR SGRLPLQPRV QLDERGRQRG DFSLWLRPAR RADAGEYRAA VHLRDRALSC RLRLRLGQAS MTASPPGSLR ASDWVILNCS FSRPDRPASV HWFRNRGQGR VPVRESPHHH LAESFLFLPQ VSPMDSGPWG CILTYRDGFN VSIMYNLTVL GLEPPTPLTV YAGAGSRVGL PCRLPAGVGT RSFLTAKWTP PGGGPDLLVT GDNGDFTLRL EDVSQAQAGT YTCHIHLQEQ QLNATVTLAI ITGQPQVGKE

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: LAG3 (AAH52589.1, 1 a.a. ~ 360 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LAG3 antibody (ABIN517422)

Quach, Metz, Thomas, Rothbard, Steinman, Ousman: "CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients." in: Multiple sclerosis (Houndmills, Basingstoke, England), Vol. 19, Issue 14, pp. 1867-77, (2013) (PubMed).

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: LAG3

Background: Full Gene Name: lymphocyte-activation gene 3
Synonyms: CD223

Gene ID: 3902

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints