LOXL1 antibody (AA 1-574)

Catalog No. ABIN517559

Product Details anti-LOXL1 Antibody

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Binding Specificity: AA 1-574

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This LOXL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Mouse polyclonal antibody raised against a full-length human LOXL1 protein.

Sequence: MALARGSRQL GALVWGACLC VLVHGQQAQP GQGSDPARWR QLIQWENNGQ VYSLLNSGSE YVPAGPQRSE SSSRVLLAGA PQAQQRRSHG SPRRRQAPSL PLPGRVGSDT VRGQARHPFG FGQVPDNWRE VAVGDSTGMA RARTSVSQQR HGGSASSVSA SAFASTYRQQ PSYPQQFPYP QAPFVSQYEN YDPASRTYDQ GFVYYRPAGG GVGAGAAAVA SAGVIYPYQP RARYEEYGGG EELPEYPPQG FYPAPERPYV PPPPPPPDGL DRRYSHSLYS EGTPGFEQAY PDPGPEAAQA HGGDPRLGWY PPYANPPPEA YGPPRALEPP YLPVRSSDTP PPGGERNGAQ QGRLSVGSVY RPNQNGRGLP DLVPDPNYVQ ASTYVQRAHL YSLRCAAEEK CLASTAYAPE ATDYDVRVLL RFPQRVKNQG TADFLPNRPR HTWEWHSCHQ HYHSMDEFSH YDLLDAATGK KVAEGHKASF CLEDSTCDFG NLKRYACTSH TQGLSPGCYD TYNADIDCQW IDITDVQPGN YILKVHVNPK YIVLESDFTN NVVRCNIHYT GRYVSATNCK IVQS

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: LOXL1 (NP_005567.2, 1 a.a. ~ 574 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LOXL1 antibody (ABIN517559)

Aung, Ozaki, Mizoguchi, Allingham, Li, Haripriya, Nakano, Uebe, Harder, Chan, Lee, Burdon, Astakhov, Abu-Amero, Zenteno, Nilgün, Zarnowski, Pakravan, Safieh, Jia, Wang, Williams, Paoli, Schlottmann et al.: "A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. ..." in: Nature genetics, Vol. 47, Issue 4, pp. 387-92, (2015) (PubMed).

Schlötzer-Schrehardt, Hammer, Krysta, Hofmann-Rummelt, Pasutto, Sasaki, Kruse, Zenkel: "LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma." in: Ophthalmology, Vol. 119, Issue 9, pp. 1832-43, (2012) (PubMed).

Target Details for LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Alternative Name: LOXL1 (LOXL1 Products)

Background: Full Gene Name: lysyl oxidase-like 1
Synonyms: LOL,LOXL

Gene ID: 4016

NCBI Accession: NM_005576