PTK6 antibody (AA 1-451)

Catalog No. ABIN519483

Cited in 3+ publications. The Mouse Polyclonal anti-PTK6 antibody (ABIN519483) specifically detects PTK6 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for PTK6 antibody (AA 1-451) (ABIN519483)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PTK6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PTK6 Antibody

Binding Specificity: AA 1-451

Purpose: Mouse polyclonal antibody raised against a full-length human PTK6 protein.

Sequence: MVSRDQAHLG PKYVGLWDFK SRTDEELSFR AGDVFHVARK EEQWWWATLL DEAGGAVAQG YVPHNYLAER ETVESEPWFF GCISRSEAVR RLQAEGNATG AFLIRVSEKP SADYVLSVRD TQAVRHYKIW RRAGGRLHLN EAVSFLSLPE LVNYHRAQSL SHGLRLAAPC RKHEPEPLPH WDDWERPREE FTLCRKLGSG YFGEVFEGLW KDRVQVAIKV ISRDNLLHQQ MLQSEIQAMK KLRHKHILAL YAVVSVGDPV YIITELMAKG SLLELLRDSD EKVLPVSELL DIAWQVAEGM CYLESQNYIH RDLAARNILV GENTLCKVGD FGLARLIKED VYLSHDHNIP YKWTAPEALS RGHYSTKSDV WSFGILLHEM FSRGQVPYPG MSNHEAFLRV DAGYRMPCPL ECPPSVHKLM LTCWCRDPEQ RPCFKALRER LSSFTSYENP T

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: PTK6 (NP_005966.1, 1 a.a. ~ 451 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PTK6 antibody (ABIN519483)

Foudah, Sallam, Akl, El Sayed: "Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors." in: European journal of medicinal chemistry, Vol. 73, pp. 310-24, (2014) (PubMed).

Sallam, Mohyeldin, Foudah, Akl, Nazzal, Meyer, Liu, El Sayed: "Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling." in: Organic & biomolecular chemistry, Vol. 12, Issue 28, pp. 5295-303, (2014) (PubMed).

Akl, Foudah, Ebrahim, Meyer, El Sayed: "The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling." in: Marine drugs, Vol. 12, Issue 4, pp. 2282-304, (2014) (PubMed).

Target Details for PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Alternative Name: PTK6

Background: Full Gene Name: PTK6 protein tyrosine kinase 6
Synonyms: BRK,FLJ42088

Gene ID: 5753

NCBI Accession: NM_005975