PTK6 antibody (AA 342-451)

Catalog No. ABIN519484

This Mouse Monoclonal antibody specifically detects PTK6 in ELISA and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for PTK6 antibody (AA 342-451) (ABIN519484)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTK6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2F11

Product Details anti-PTK6 Antibody

Binding Specificity: AA 342-451

Purpose: Mouse monoclonal antibody raised against a partial recombinant PTK6.

Sequence: YLSHDHNIPY KWTAPEALSR GHYSTKSDVW SFGILLHEMF SRGQVPYPGM SNHEAFLRVD AGYRMPCPLE CPPSVHKLML TCWCRDPEQR PCFKALRERL SSFTSYENPT

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PTK6 (NP_005966, 342 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PTK6 antibody (ABIN519484)

Akl, Ayoub, Mohyeldin, Busnena, Foudah, Liu, Sayed: "Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models." in: PLoS ONE, Vol. 9, Issue 5, pp. e97622, (2014) (PubMed).

Falkenberg, Anastasov, Höfig, Bashkueva, Lindner, Höfler, Rosemann, Aubele: "Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo." in: Molecular oncology, Vol. 9, Issue 1, pp. 282-94, (2014) (PubMed).

Target Details for PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Alternative Name: PTK6

Background: Full Gene Name: PTK6 protein tyrosine kinase 6
Synonyms: BRK,FLJ42088

Gene ID: 5753

NCBI Accession: NM_005975