Retinoic Acid Receptor alpha antibody (AA 315-424)

Catalog No. ABIN519635

The Mouse Monoclonal anti-Retinoic Acid Receptor alpha antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect Retinoic Acid Receptor alpha in samples from Human. There is 1 publication available.

Quick Overview for Retinoic Acid Receptor alpha antibody (AA 315-424) (ABIN519635)

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoic Acid Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2D2

Product Details anti-Retinoic Acid Receptor alpha Antibody

Binding Specificity: AA 315-424

Purpose: Mouse monoclonal antibody raised against a partial recombinant RARA.

Sequence: QLLPLEMDDA ETGLLSAICL ICGDRQDLEQ PDRVDMLQEP LLEALKVYVR KRRPSRPHMF PKMLMKITDL RSISAKGAER VITLKMEIPG SMPPLIQEML ENSEGLDTLS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RARA (NP_000955, 315 a.a. ~ 424 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Retinoic Acid Receptor alpha antibody (ABIN519635)

Voss, Collin, Dixon, Thomas: "Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity." in: Developmental cell, Vol. 17, Issue 5, pp. 674-86, (2009) (PubMed).

Target Details for Retinoic Acid Receptor alpha

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Alternative Name: RARA

Background: Full Gene Name: retinoic acid receptor, alpha
Synonyms: NR1B1,RAR

Gene ID: 5914

NCBI Accession: NM_000964

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins