SPR antibody (AA 1-261)

Catalog No. ABIN520456

This Mouse Polyclonal antibody specifically detects SPR in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for SPR antibody (AA 1-261) (ABIN520456)

Target: SPR (Sepiapterin Reductase (SPR))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This SPR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPR Antibody

Binding Specificity: AA 1-261

Purpose: Mouse polyclonal antibody raised against a full-length human SPR protein.

Sequence: MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS MLCLTSSVLK AFPDSPGLNR TVVNISSLCA LQPFKGWALY CAGKAARDML FQVLALEEPN VRVLNYAPGP LDTDMQQLAR ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD K

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SPR (AAH17310.1, 1 a.a. ~ 261 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SPR antibody (ABIN520456)

Lange, Geerts, Feith, Mocz, Koster, Bachmann: "Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation." in: Journal of molecular biology, Vol. 426, Issue 2, pp. 332-46, (2014) (PubMed).

Target Details for SPR

Target: SPR (Sepiapterin Reductase (SPR))

Alternative Name: SPR

Background: Full Gene Name: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms: SDR38C1

Gene ID: 6697

NCBI Accession: NM_003124

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration