UMPS antibody (AA 381-479)

Catalog No. ABIN521260

This Mouse Monoclonal antibody specifically detects UMPS in WB, ELISA and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for UMPS antibody (AA 381-479) (ABIN521260)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UMPS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2B10

Product Details anti-UMPS Antibody

Binding Specificity: AA 381-479

Purpose: Mouse monoclonal antibody raised against a partial recombinant UMPS.

Sequence: DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLG

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: UMPS (NP_000364, 381 a.a. ~ 479 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-UMPS antibody (ABIN521260)

Griffith, Mwenifumbo, Cheung, Paul, Pugh, Tang, Chittaranjan, Morin, Asano, Ally, Miao, Lee, Chan, Taylor, Severson, Hou, Griffith, Cheng, Novik, Moore, Luk, Owen, Brown, Morin, Gill, Tai, Marra: "Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer." in: The pharmacogenomics journal, Vol. 13, Issue 2, pp. 148-58, (2013) (PubMed).

Target Details for UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Alternative Name: UMPS

Background: Full Gene Name: uridine monophosphate synthetase
Synonyms: OPRT

Gene ID: 7372

NCBI Accession: NM_000373

Pathways: Ribonucleoside Biosynthetic Process