ROCK2 antibody (AA 1279-1388)

Catalog No. ABIN522961

This Mouse Monoclonal antibody specifically detects ROCK2 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for ROCK2 antibody (AA 1279-1388) (ABIN522961)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ROCK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1E12

Product Details anti-ROCK2 Antibody

Binding Specificity: AA 1279-1388

Purpose: Mouse monoclonal antibody raised against a partial recombinant ROCK2.

Sequence: KPLWHMFKPP PALECRRCHI KCHKDHMDKK EEIIAPCKVY YDISTAKNLL LLANSTEEQQ KWVSRLVKKI PKKPPAPDPF ARSSPRTSMK IQQNQSIRRP SRQLAPNKPS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ROCK2 (NP_004841, 1279 a.a. ~ 1388 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ROCK2 antibody (ABIN522961)

Chen, Liu, Huang, Chiou: "Vascular hyperpermeability in response to inflammatory mustard oil is mediated by Rho kinase in mice systemically exposed to arsenic." in: Microvascular research, Vol. 82, Issue 2, pp. 182-9, (2011) (PubMed).

Target Details for ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Alternative Name: ROCK2

Background: Full Gene Name: Rho-associated, coiled-coil containing protein kinase 2
Synonyms: KIAA0619

Gene ID: 9475

NCBI Accession: NM_004850

Pathways: Microtubule Dynamics, WNT Signaling, Tube Formation