ZEB2 antibody (AA 1115-1214)

Catalog No. ABIN523264

This Mouse Monoclonal antibody specifically detects ZEB2 in WB, ELISA and IF. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for ZEB2 antibody (AA 1115-1214) (ABIN523264)

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2D12

Product Details anti-ZEB2 Antibody

Binding Specificity: AA 1115-1214

Purpose: Mouse monoclonal antibody raised against a partial recombinant ZFHX1B.

Sequence: SITPQGYSDS EERESMPRDG ESEKEHEKEG EDGYGKLGRQ DGDEEFEEEE EESENKSMDT DPETIRDEEE TGDHSMDDSS EDGKMETKSD HEEDNMEDGM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ZFHX1B (NP_055610.1, 1115 a.a. ~ 1214 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ZEB2 antibody (ABIN523264)

Konradi, Yasmin, Haslwanter, Weber, Gesslbauer, Sixt, Strobl: "Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2." in: European journal of immunology, Vol. 44, Issue 2, pp. 553-60, (2014) (PubMed).

Pogribny, Muskhelishvili, Tryndyak, Beland: "The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation." in: Toxicology and applied pharmacology, Vol. 235, Issue 3, pp. 305-11, (2009) (PubMed).

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2

Background: Full Gene Name: zinc finger E-box binding homeobox 2
Synonyms: KIAA0569,SIP-1,SIP1,SMADIP1,ZFHX1B

Gene ID: 9839

NCBI Accession: NM_014795

Pathways: Tube Formation