Superoxide dismutase copper chaperone antibody (AA 175-274)

Catalog No. ABIN523352

The Mouse Monoclonal anti-Superoxide dismutase copper chaperone antibody has been validated for WB, ELISA, IP, IF and IHC (p). It is suitable to detect Superoxide dismutase copper chaperone in samples from Human. There is 1 publication available.

Quick Overview for Superoxide dismutase copper chaperone antibody (AA 175-274) (ABIN523352)

Target: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Superoxide dismutase copper chaperone antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1E2

Product Details anti-Superoxide dismutase copper chaperone Antibody

Binding Specificity: AA 175-274

Purpose: Mouse monoclonal antibody raised against a partial recombinant CCS.

Sequence: ADGRAIFRME DEQLKVWDVI GRSLIIDEGE DDLGRGGHPL SKITGNSGER LACGIIARSA GLFQNPKQIC SCDGLTIWEE RGRPIAGKGR KESAQPPAHL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CCS (NP_005116, 175 a.a. ~ 274 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Superoxide dismutase copper chaperone antibody (ABIN523352)

Spinazzi, Sghirlanzoni, Salviati, Angelini: "Impaired copper and iron metabolism in blood cells and muscles of patients affected by copper deficiency myeloneuropathy." in: Neuropathology and applied neurobiology, Vol. 40, Issue 7, pp. 888-98, (2014) (PubMed).

Target Details for Superoxide dismutase copper chaperone

Target: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Alternative Name: CCS

Background: Full Gene Name: copper chaperone for superoxide dismutase
Synonyms: MGC138260

Gene ID: 9973

NCBI Accession: NM_005125

Pathways: Transition Metal Ion Homeostasis