KDM5B antibody (AA 231-319)

Catalog No. ABIN524185

This Mouse Polyclonal antibody specifically detects KDM5B in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for KDM5B antibody (AA 231-319) (ABIN524185)

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This KDM5B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KDM5B Antibody

Binding Specificity: AA 231-319

Purpose: Mouse polyclonal antibody raised against a partial recombinant KDM5B.

Sequence: AKRMRAEAMN IKIEPEETTE ARTHNLRRRM GCPTPKCENE KEMKSSIKQE PIERKDYIVE NEKEKPKSRS KKATNAVDLY VCLLCGSGN

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: KDM5B (NP_006609, 231 a.a. ~ 319 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-KDM5B antibody (ABIN524185)

Bamodu, Huang, Lee, Wu, Wang, Hsiao, Yeh, Chao: "Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448." in: BMC cancer, Vol. 16, pp. 160, (2016) (PubMed).

Xiang, Zhu, Han, Ye, Xu, Peng, Ma, Yu, Lin, Chen, Chen: "JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 49, pp. 19226-31, (2007) (PubMed).

Target Details for KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Alternative Name: KDM5B

Background: Full Gene Name: jumonji, AT rich interactive domain 1B
Synonyms: FLJ10538,FLJ12459,FLJ12491,FLJ16281,FLJ23670,KDM5B,PLU-1,PUT1,RBBP2H1A

Gene ID: 10765

NCBI Accession: NM_006618

Pathways: Warburg Effect