LIM Domain Binding 3 Protein antibody (AA 1-283)

Catalog No. ABIN524582

The Mouse Monoclonal anti-LIM Domain Binding 3 Protein antibody has been validated for WB, ELISA, IF and RNAi. It is suitable to detect LIM Domain Binding 3 Protein in samples from Human. There are 2+ publications available.

Quick Overview for LIM Domain Binding 3 Protein antibody (AA 1-283) (ABIN524582)

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LIM Domain Binding 3 Protein antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)

Clone: 3C8

Product Details anti-LIM Domain Binding 3 Protein Antibody

Binding Specificity: AA 1-283

Purpose: Mouse monoclonal antibody raised against a full-length recombinant LDB3.

Sequence: MSYSVTLTGP GPWGFRLQGG KDFNMPLTIS RITPGSKAAQ SQLSQGDLVV AIDGVNTDTM THLEAQNKIK SASYNLSLTL QKSKRPIPIS TTAPPVQTPL PVIPHQKVVV NSPANADYQE RFNPSALKDS ALSTHKPIEV KGLGGKATII HAQYNTPISM YSQDAIMDAI AGQAQAQGSD FSGSLPIKDL AVDSASPVYQ AVIKSQNKPE DEADEWARRS SNLQSRSFRI LAQMTGTEFM QDPDEEALRR SRERFETERN SPRFAKLRNW HHGLSAQILN VKS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: LDB3 (AAH10929, 1 a.a. ~ 283 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LIM Domain Binding 3 Protein antibody (ABIN524582)

Lin, Ruiz, Bajraktari, Ohman, Banerjee, Gribble, Kaufman, Wingfield, Griggs, Fischbeck, Mankodi: "Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13615-26, (2014) (PubMed).

Arimura, Inagaki, Hayashi, Shichi, Sato, Hinohara, Vatta, Towbin, Chikamori, Yamashina, Kimura: "Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy." in: Cardiovascular research, Vol. 83, Issue 1, pp. 80-8, (2009) (PubMed).

Target Details for LIM Domain Binding 3 Protein

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Alternative Name: LDB3

Background: Full Gene Name: LIM domain binding 3
Synonyms: CYPHER,FLJ35865,KIAA01613,KIAA0613,ORACLE,PDLIM6,ZASP,ldb3z1,ldb3z4

Gene ID: 11155