DKK1 antibody (AA 1-266)

Catalog No. ABIN524877

Cited in 1 publication. The Mouse Monoclonal anti-DKK1 antibody (Clone 2B12) (ABIN524877) specifically detects DKK1 in WB, ELISA, IP and IHC (p). The antibody is reactive with Human samples.

Quick Overview for DKK1 antibody (AA 1-266) (ABIN524877)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DKK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2B12

Product Details anti-DKK1 Antibody

Binding Specificity: AA 1-266

Purpose: Mouse monoclonal antibody raised against a full length recombinant DKK1.

Sequence: MMALGAAGAT RVSVAMVAAA LGGHPLLGVS ATLNSVLNSN AIKNLPPPLG GAAGHPGSAV SAAPGILYPG GNKYQTIDNY QPYPCAEDEE CGTDEYCASP TRGGDAGVQI CLACRKRRKR CMRHAMCCPG NYCKNGICVS SDQNHFRGEI EETITESFGN DHSTLDGYSR RTTLSSKMYH TTGQEGSVCL RSSDCASGLC CARHFWSKIC KPVLKGGQVC TKHRRKGSHG LEIFQRCYCG EGLSCRIQKD HHQASNSSRL HTCQRH

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DKK1 (AAH01539.1, 1 a.a. ~ 266 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DKK1 antibody (ABIN524877)

Brunetti, Faienza, Piacente, Ventura, Oranger, Carbone, Benedetto, Colaianni, Gigante, Mori, Gesualdo, Colucci, Cavallo, Grano: "High dickkopf-1 levels in sera and leukocytes from children with 21-hydroxylase deficiency on chronic glucocorticoid treatment." in: American journal of physiology. Endocrinology and metabolism, Vol. 304, Issue 5, pp. E546-54, (2013) (PubMed).

Target Details for DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Alternative Name: DKK1

Background: Full Gene Name: dickkopf homolog 1 (Xenopus laevis)
Synonyms: DKK-1,SK

Gene ID: 22943

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation