SMG1 antibody (AA 2922-3031)
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- Target See all SMG1 Antibodies
- SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))
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Binding Specificity
- AA 2922-3031
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SMG1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Mouse monoclonal antibody raised against a partial recombinant SMG1.
- Sequence
- PDVMSQNARK LIQKNLATSA DTPPSTVPGT GKSVACSPKK AVRDPKTGKA VQERNSYAVS VWKRVKAKLE GRDVDPNRRM SVAEQVDYVI KEATNLDNLA QLYEGWTAWV
- Cross-Reactivity
- Human
- Characteristics
- Antibody Reactive Against Recombinant Protein.
- Immunogen
- SMG1 (NP_055535, 2922 a.a. ~ 3031 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Clone
- 1A8
- Isotype
- IgG2a
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- In 1x PBS, pH 7.4
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8." in: Genes & development, Vol. 25, Issue 2, pp. 153-64, (2011) (PubMed).
: "Processing bodies are not required for mammalian nonsense-mediated mRNA decay." in: RNA (New York, N.Y.), Vol. 15, Issue 7, pp. 1265-73, (2009) (PubMed).
: "
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The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8." in: Genes & development, Vol. 25, Issue 2, pp. 153-64, (2011) (PubMed).
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- Target
- SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))
- Alternative Name
- SMG1 (SMG1 Products)
- Background
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Full Gene Name: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Synonyms: 61E3.4,ATX,KIAA0421,LIP - Gene ID
- 23049
- NCBI Accession
- NM_014006
- Pathways
- Inositol Metabolic Process
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