Ceramide Synthase 2 antibody (AA 1-380)

Catalog No. ABIN526188

Cited in 1 publication. The Mouse Polyclonal anti-Ceramide Synthase 2 antibody (ABIN526188) specifically detects Ceramide Synthase 2 in WB. The antibody is reactive with Human samples.

Quick Overview for Ceramide Synthase 2 antibody (AA 1-380) (ABIN526188)

Target: Ceramide Synthase 2 (CERS2)

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This Ceramide Synthase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ceramide Synthase 2 Antibody

Binding Specificity: AA 1-380

Purpose: Mouse polyclonal antibody raised against a full-length human LASS2 protein.

Sequence: MLQTLYDYFW WERLWLPVNL TWADLEDRDG RVYAKASDLY ITLPLALLFL IVRYFFELYV ATPLAALLNI KEKTRLRAPP NATLEHFYLT SGKQPKQVEV ELLSRQSGLS GRQVERWFRR RRNQDRPSLL KKFREASWRF TFYLIAFIAG MAVIVDKPWF YDMKKVWEGY PIQSTIPSQY WYYMIELSFY WSLLFSIASD VKRKDFKEQI IHHVATIILI SFSWFANYIR AGTLIMALHD SSDYLLESAK MFNYAGWKNT CNNIFIVFAI VFIITRLVIL PFWILHCTLV YPLELYPAFF GYYFFNSMMG VLQLLHIFWA YLILRMAHKF ITGKLVEDER SDREETESSE GEEAAAGGGA KSRPLANGHP ILNNNHRKND

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: LASS2 (NP_071358.1, 1 a.a. ~ 380 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Ceramide Synthase 2 antibody (ABIN526188)

Jensen, Calvert, Volpert, Kouri, Hurley, Luciano, Wu, Chalastanis, Futerman, Stegh: "Bcl2L13 is a ceramide synthase inhibitor in glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 15, pp. 5682-7, (2014) (PubMed).

Target Details for Ceramide Synthase 2

Target: Ceramide Synthase 2 (CERS2)

Alternative Name: LASS2

Background: Full Gene Name: LAG1 homolog, ceramide synthase 2
Synonyms: CerS2,FLJ10243,L3,MGC987,SP260,TMSG1

Gene ID: 29956

NCBI Accession: NM_022075