WDR19 antibody (AA 1-437)

Catalog No. ABIN528302

Product Details anti-WDR19 Antibody

Target: WDR19 (WD Repeat Domain 19 (WDR19))

Binding Specificity: AA 1-437

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This WDR19 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Mouse polyclonal antibody raised against a full-length human WDR19 protein.

Sequence: MKRIFSLLEK TWLGAPIQFA WQKTSGNYLA VTGADYIVKI FDRHGQKRSE INLPGNCVAM DWDKDGDVLA VIAEKSSCIY LWDANTNKTS QLDNGMRDQM SFLLWSKVGS FLAVGTVKGN LLIYNHQTSR KIPVLGKHTK RITCGCWNAE NLLALGGEDK MITVSNQEGD TIRQTQVRSE PSNMQFFLMK MDDRTSAAES MISVVLGKKT LFFLNLNEPD NPADLEFQQD FGNIVCYNWY GDGRIMIGFS CGHFVVISTH TGELGQEIFQ ARNHKDNLTS IAVSQTLNKV ATCGDNCIKI QDLVDLKDMY VILNLDEENK GLGTLSWTDD GQLLALSTQR GSLHVFLTKL PILGDACSTR IAYLTSLLEV TVANPVEGEL PITVSVDVEP NFVAVGLYHL AVGMNNRAWF YVLGENAVKK IERYGVSGNS SQYLPSF

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: WDR19 (AAH32578.1, 1 a.a. ~ 437 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-WDR19 antibody (ABIN528302)

Chaya, Omori, Kuwahara, Furukawa: "ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport." in: The EMBO journal, Vol. 33, Issue 11, pp. 1227-42, (2014) (PubMed).

Ashe, Butterfield, Town, Courtney, Cooper, Ferguson, Barry, Olsson, Liem, Parton, Wainwright, Anderson, Whitelaw, Wicking: "Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies." in: Human molecular genetics, Vol. 21, Issue 8, pp. 1808-23, (2012) (PubMed).

Bredrup, Saunier, Oud, Fiskerstrand, Hoischen, Brackman, Leh, Midtbø, Filhol, Bole-Feysot, Nitschké, Gilissen, Haugen, Sanders, Stolte-Dijkstra, Mans, Steenbergen, Hamel, Matignon, Pfundt, Jeanpierre et al.: "Ciliopathies with skeletal anomalies and renal insufficiency due to mutations in the IFT-A gene WDR19. ..." in: American journal of human genetics, Vol. 89, Issue 5, pp. 634-43, (2011) (PubMed).

Target Details for WDR19

Target: WDR19 (WD Repeat Domain 19 (WDR19))

Alternative Name: WDR19 (WDR19 Products)

Background: Full Gene Name: WD repeat domain 19
Synonyms: FLJ23127,KIAA1638,ORF26,PWDMP

Gene ID: 57728

Pathways: Hedgehog Signaling