Septin 12 antibody (AA 1-358)

Catalog No. ABIN530515

This Mouse Polyclonal antibody specifically detects Septin 12 in WB, IF and IHC (p). It exhibits reactivity toward Human and has been mentioned in 4+ publications.

Quick Overview for Septin 12 antibody (AA 1-358) (ABIN530515)

Target: Septin 12 (Sep12)

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This Septin 12 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Septin 12 Antibody

Binding Specificity: AA 1-358

Purpose: Mouse polyclonal antibody raised against a full-length human SEPT12 protein.

Sequence: MDPLRRSPSP CLSSQPSSPS TPPCEMLGPV GIEAVLDQLK IKAMKMGFEF NIMVVGQSGL GKSTMVNTLF KSKVWKSNPP GLGVPTPQTL QLHSLTHVIE EKGVKLKLTV TDTPGFGDQI NNDNCWDPIL GYINEQYEQY LQEEILITRQ RHIPDTRVHC CVYFVPPTGH CLRPLDIEFL QRLCRTVNVV PVIARADSLT MEEREAFRRR IQQNLRTHCI DVYPQMCFDE DINDKILNSK LRDRIPFAVV GADQEHLVNG RCVLGRKTKW GIIEVENMAH CEFPLLRDLL IRSHLQDLKD ITHNIHYENY RVIRLNESHL LPRGPGWVNL APASPGQLTT PRTFKVCRGA HDDSDDEF

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SEPT12 (AAH35619.1, 1 a.a. ~ 358 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Septin 12 antibody (ABIN530515)

Lai, Wu, Wang, Chen, Wang, Chen, Wu, Chiang, Kuo, Lin: "SEPT12-NDC1 Complexes Are Required for Mammalian Spermiogenesis." in: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).

Kuo, Chiang, Wang, Kuo, Chen, Yu, Teng, Lin, Lin: "SEPT12-microtubule complexes are required for sperm head and tail formation." in: International journal of molecular sciences, Vol. 14, Issue 11, pp. 22102-16, (2013) (PubMed).

Kuo, Lin, Chen, Wang, Chiou, Lin, Pan, Wu, Su, Hsu, Kuo: "SEPT12 mutations cause male infertility with defective sperm annulus." in: Human mutation, Vol. 33, Issue 4, pp. 710-9, (2012) (PubMed).

Lin, Wang, Chen, Kuo, Chiou, Lin, Wu, Hsu, Chiang, Kuo: "SEPTIN12 genetic variants confer susceptibility to teratozoospermia." in: PLoS ONE, Vol. 7, Issue 3, pp. e34011, (2012) (PubMed).

Target Details for Septin 12

Target: Septin 12 (Sep12)

Alternative Name: SEPT12

Background: Full Gene Name: septin 12
Synonyms: FLJ25410

Gene ID: 124404