ELOVL1 antibody (N-Term)

Catalog No. ABIN5514396

This Rabbit Polyclonal antibody specifically detects ELOVL1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse and Zebrafish (Danio rerio).

Quick Overview for ELOVL1 antibody (N-Term) (ABIN5514396)

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ELOVL1 Antibody

Binding Specificity: N-Term

Sequence: RGFMIVYNFS LVALSLYIVY EFLMSGWLST YTWRCDPVDY SNSPEALRMV

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ELOV1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ELOV1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELOVL1

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Alternative Name: ELOV1

Background: ELOV1 is a condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). It exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. It is important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Alias Symbols: ELOVL1, SSC1, CGI-88,

Protein Interaction Partner: UBC, HSD17B12, CERS2, TECR, GLP1R, TWF2, PSMD10,

Protein Size: 279

Gene ID: 64834

NCBI Accession: NP_073732

UniProt: Q9BW60