PDLIM2 antibody (N-Term)

Catalog No. ABIN5514410

Product Details anti-PDLIM2 Antibody

Target: PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LHAEAQSKIR QSPSPLRLQL DRSQATSPGQ TNGDSSLEVL ATRFQGSVRT

Characteristics: This is a rabbit polyclonal antibody against PDLI2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDLI2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDLIM2

Target: PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))

Alternative Name: PDLI2 (PDLIM2 Products)

Background: This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alias Symbols: PDLIM2, PP6345,

Protein Interaction Partner: ACD, POT1, UBC, RELA,

Protein Size: 352

Gene ID: 64236

UniProt: Q96JY6