TMPS2 antibody (C-Term)

Catalog No. ABIN5514431

This anti-TMPS2 antibody is a Rabbit Polyclonal antibody detecting TMPS2 in WB. Suitable for Human, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rabbit, Rat and Zebrafish (Danio rerio).

Quick Overview for TMPS2 antibody (C-Term) (ABIN5514431)

Target: TMPS2 (Transmembrane Protease, Serine 2 (TMPS2))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMPS2 Antibody

Binding Specificity: C-Term

Sequence: GAGYQVEKVI SHPNYDSKTK NNDIALMKLQ KPLTFNDLVK PVCLPNPGMM

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against TMPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TMPS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMPS2

Target: TMPS2 (Transmembrane Protease, Serine 2 (TMPS2))

Alternative Name: TMPS2

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: TMPRSS2, PRSS10,

Protein Interaction Partner: TMPRSS2,

Protein Size: 492

Gene ID: 7113

NCBI Accession: NP_005647

UniProt: O15393