TMPS2 antibody (N-Term)
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- Target See all TMPS2 products
- TMPS2 (Transmembrane Protease, Serine 2 (TMPS2))
- Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TMPS2 antibody is un-conjugated
- Application
- Western Blotting (WB)
- Sequence
- YYENHGYQPE NPYPAQPTVV PTVYEVHPAQ YYPSPVPQYA PRVLTQASNP
- Characteristics
- This is a rabbit polyclonal antibody against TMPS2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TMPS2
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TMPS2 (Transmembrane Protease, Serine 2 (TMPS2))
- Alternative Name
- TMPS2 (TMPS2 Products)
- Background
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This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TMPRSS2, PRSS10,
Protein Interaction Partner: TMPRSS2,
Protein Size: 492 - Gene ID
- 7113
- NCBI Accession
- NP_005647
- UniProt
- O15393
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