Peroxisomal Bifunctional Enzyme antibody (Middle Region)

Catalog No. ABIN5514454

The Rabbit Polyclonal anti-Peroxisomal Bifunctional Enzyme antibody is suitable to detect Peroxisomal Bifunctional Enzyme in samples from Human. It has been validated for WB.

Quick Overview for Peroxisomal Bifunctional Enzyme antibody (Middle Region) (ABIN5514454)

Target: Peroxisomal Bifunctional Enzyme (ECHP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details anti-Peroxisomal Bifunctional Enzyme Antibody

Binding Specificity: Middle Region

Sequence: VIAVDSDKNQ LATANKMITS VLEKEASKMQ QSGHPWSGPK PRLTSSVKEL

Characteristics: This is a rabbit polyclonal antibody against ECHP. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ECHP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxisomal Bifunctional Enzyme

Target: Peroxisomal Bifunctional Enzyme (ECHP)

Alternative Name: ECHP

Background: The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: EHHADH, ECHD,

Protein Size: 723

Gene ID: 1962

NCBI Accession: NP_001957

UniProt: Q08426