DGCR6 antibody (C-Term)

Catalog No. ABIN5514722

This anti-DGCR6 antibody is a Rabbit Polyclonal antibody detecting DGCR6 in WB. Suitable for Human.

Quick Overview for DGCR6 antibody (C-Term) (ABIN5514722)

Target: DGCR6 (DiGeorge Syndrome Critical Region Gene 6 (DGCR6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGCR6 Antibody

Binding Specificity: C-Term

Sequence: REEQRAMDQK IVLELDRKVA DQQSTLEKAG VAGFYVTTNP QELMLQMNLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DGCR6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DGCR6

Target: DGCR6 (DiGeorge Syndrome Critical Region Gene 6 (DGCR6))

Alternative Name: DGCR6

Background: DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia.

Protein Interaction Partner: NOTCH2NL, C3orf62, CCDC36, RFX6, SPERT, CCDC67, MIPOL1, RIMBP3, FBF1, C1orf94, LZTS2, ENKD1, DOCK8, EFHC2, CCDC33, CBLL1, PRDM14, KLHL12, HOMEZ, KIAA1377, ZNF398, AGTRAP, ZC4H2, ZNF446, NECAB2, ADAMTSL4, NUP54, MBIP, EFEMP2, RABGEF1, TUBGCP4, SS18L1, TFIP

Protein Size: 220

Gene ID: 8214

NCBI Accession: NM_005675, NP_005666

UniProt: Q14129