RPS19 antibody (C-Term)

Catalog No. ABIN5514788

This anti-RPS19 antibody is a Rabbit Polyclonal antibody detecting RPS19 in WB. Suitable for Human.

Quick Overview for RPS19 antibody (C-Term) (ABIN5514788)

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS19 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPS19 Antibody

Binding Specificity: C-Term

Sequence: SKSVARRVLQ ALEGLKMVEK DQDGGRKLTP QGQRDLDRIA GQVAAANKKH

Characteristics: This is a rabbit polyclonal antibody against RS19. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RS19

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPS19

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Alternative Name: RS19

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Alias Symbols: RPS19,

Protein Interaction Partner: TP53, HUWE1, CEP250, NEDD1, TUBGCP4, TUBGCP2, PPP2R1A, AURKA, UBC, MDM2, RPS17, RNF2, WIBG, EIF2A, TSR1, SERBP1, EIF3E, FAU, RPS29, RPS28, RPS26, RPS25, RPS24, RPS23, RPS20, RPS18, RPS16, RPS15A, RPS15, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6,

Protein Size: 145

Gene ID: 6223

NCBI Accession: NP_001013

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly