Cathepsin S antibody (Middle Region)

Catalog No. ABIN5514808

The Rabbit Polyclonal anti-Cathepsin S antibody has been validated for WB. It is suitable to detect Cathepsin S in samples from Human, Mouse, Cow, Rat, Horse, Dog, Guinea Pig, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for Cathepsin S antibody (Middle Region) (ABIN5514808)

Target: Cathepsin S (CTSS)

Reactivity: Human, Mouse, Cow, Rat, Horse, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin S antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin S Antibody

Binding Specificity: Middle Region

Sequence: EAQLKLKTGK LVSLSAQNLV DCSTEKYGNK GCNGGFMTTA FQYIIDNKGI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 83%, Rabbit: 93%, Rat: 87%, Sheep: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CATS. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CATS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cathepsin S

Target: Cathepsin S (CTSS)

Alternative Name: CATS

Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alias Symbols: CTSS,

Protein Size: 331

Gene ID: 1520

NCBI Accession: NP_004070

UniProt: P25774

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades