Glutathione Synthetase antibody (C-Term)

Catalog No. ABIN5514831

This Rabbit Polyclonal antibody specifically detects Glutathione Synthetase in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Cow, Goat and Zebrafish (Danio rerio).

Quick Overview for Glutathione Synthetase antibody (C-Term) (ABIN5514831)

Target: Glutathione Synthetase (GSS)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Cow, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutathione Synthetase Antibody

Binding Specificity: C-Term

Sequence: EEGDQAIAEA LAAPSRFVLK PQREGGGNNL YGEEMVQALK QLKDSEERAS

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GSS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GSS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Alias Symbols: GSS,

Protein Interaction Partner: GSS, UBC, GINS3, OLA1, DCPS, ABHD14A, RRAGB, PDIA4, USP14, YWHAH, YWHAG, YWHAE, YWHAB, VCL, RAP1GDS1, PPP5C, PAFAH1B2, MVK, MSN, HMGB3, ECHS1, TBCB, ASS1, ASNS, CDK9, TERF1, GSTZ1,

Protein Size: 474

Gene ID: 2937

NCBI Accession: XP_005260463

UniProt: P48637

Pathways: Warburg Effect