MYRIP antibody (Middle Region)

Catalog No. ABIN5514958

The Rabbit Polyclonal anti-MYRIP antibody is suitable to detect MYRIP in samples from Human, Dog, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for MYRIP antibody (Middle Region) (ABIN5514958)

Target: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Reactivity: Human, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYRIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYRIP Antibody

Binding Specificity: Middle Region

Sequence: RRARLGSEEP SKEPSSPSAQ LRDLDTHQVS DDLSETDISN EARDPQTLTD

Predicted Reactivity: Dog: 86%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against MYRIP. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MYRIP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYRIP

Target: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Alternative Name: MYRIP

Background: MYRIP is a rab effector protein involved in melanosome transport. It Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. It functions as a protein kinase A-anchoring protein (AKAP). It may act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).

Alias Symbols: MYRIP, SLAC2C,

Protein Interaction Partner: C1orf216, Dlg4, RAB27A, MYO7A,

Protein Size: 672

Gene ID: 25924

Pathways: Positive Regulation of Peptide Hormone Secretion