Peroxiredoxin 5 antibody (Middle Region)

Catalog No. ABIN5515051

The Rabbit Polyclonal anti-Peroxiredoxin 5 antibody has been validated for WB. It is suitable to detect Peroxiredoxin 5 in samples from Human, Mouse, Rat, Goat, Dog, Guinea Pig, Horse, Sheep, Cow and Zebrafish (Danio rerio).

Quick Overview for Peroxiredoxin 5 antibody (Middle Region) (ABIN5515051)

Target: Peroxiredoxin 5 (PRDX5)

Reactivity: Human, Mouse, Rat, Goat, Dog, Guinea Pig, Horse, Sheep, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Peroxiredoxin 5 Antibody

Binding Specificity: Middle Region

Sequence: VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI

Predicted Reactivity: Cow: 86%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Sheep: 86%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against PRDX5. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRDX5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxiredoxin 5

Target: Peroxiredoxin 5 (PRDX5)

Alternative Name: PRDX5

Background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.

Alias Symbols: ACR1, SBBI10

Protein Interaction Partner: UBC, MDM2, WWOX, ATF2, PEX5, TOMM40, PRDX6, STAM, SUMO1, UBE2B, UBE2A, PRDX2, VAMP2, SOD1, RPS12, RAD23B, PTMS, PRDX1, MDH1, IGBP1, APP, ZFYVE19, PSRC1, GINS4, UBAP2, PTPN23, PTGR1, PARK7, IFT27, SEC24A, SSSCA1, ICT1, BABAM1, CCDC90B,

Protein Size: 162

Gene ID: 25824

Pathways: Cell RedoxHomeostasis