Syndecan 1 antibody (N-Term)
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- Target See all Syndecan 1 (SDC1) Antibodies
- Syndecan 1 (SDC1)
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Syndecan 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LWLWLCALAL SLQPALPQIV ATNLPPEDQD GSGDDSDNFS GSGAGALQDI
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SDC1
- Top Product
- Discover our top product SDC1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Syndecan 1 (SDC1)
- Alternative Name
- SDC1 (SDC1 Products)
- Background
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The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Alias Symbols: SDC, CD138, SYND1, syndecan
Protein Size: 310 - Gene ID
- 6382
- NCBI Accession
- NM_001006946, NP_001006947
- UniProt
- P18827
- Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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