AXIN2 antibody (N-Term)

Catalog No. ABIN5515390

The Rabbit Polyclonal anti-AXIN2 antibody has been validated for WB. It is suitable to detect AXIN2 in samples from Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Cow and Zebrafish (Danio rerio).

Quick Overview for AXIN2 antibody (N-Term) (ABIN5515390)

Target: AXIN2 (Axin 2 (AXIN2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXIN2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AXIN2 Antibody

Binding Specificity: N-Term

Sequence: FRTFLEREKC VDTLDFWFAC NGFRQMNLKD TKTLRVAKAI YKRYIENNSI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against AXIN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human AXIN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AXIN2

Target: AXIN2 (Axin 2 (AXIN2))

Alternative Name: AXIN2

Background: AXIN2 is an inhibitor of the Wnt signaling pathway. It down-regulates beta-catenin. It probably facilitate the phosphorylation of beta- catenin and APC by GSK3B.

Alias Symbols: AXIN2,

Protein Interaction Partner: FBXW11, GSK3B, GSK3A, UBC, CDC20, AXIN1, KDM5B, ANKRD6, SMAD3, CSNK1E, APC, CTNNB1, APC2, ESR1,

Protein Size: 843

Gene ID: 8313

NCBI Accession: NP_004646

UniProt: Q9Y2T1

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling