NEFH antibody (C-Term)

Catalog No. ABIN5515615

The Rabbit Polyclonal anti-NEFH antibody has been validated for WB. It is suitable to detect NEFH in samples from Human.

Quick Overview for NEFH antibody (C-Term) (ABIN5515615)

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEFH Antibody

Binding Specificity: C-Term

Sequence: KPEEKPKTEA KAKEDDKTLS KEPSKPKAEK AEKSSSTDQK DSKPPEKATE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NEFH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEFH

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Alternative Name: NEFH

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Alias Symbols: NFH

Protein Size: 963

Gene ID: 4744