PCDHb5 antibody (N-Term)

Catalog No. ABIN5515617

This Rabbit Polyclonal antibody specifically detects PCDHb5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig and Rabbit.

Quick Overview for PCDHb5 antibody (N-Term) (ABIN5515617)

Target: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHb5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHb5 Antibody

Binding Specificity: N-Term

Sequence: QFFQTDLQLT DINDHAPEFP EKEMLLKIPE STQPGTVFPL KIAQDFDIGS

Predicted Reactivity: Cow: 77%, Guinea Pig: 85%, Human: 100%, Mouse: 92%, Rabbit: 75%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PCDHB5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PCDHB5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCDHb5

Target: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Alternative Name: PCDHB5

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Alias Symbols: PCDHB5,

Protein Interaction Partner: UBC, DGKB,

Protein Size: 795

Gene ID: 26167

NCBI Accession: NP_056484

UniProt: Q9Y5E4