PCDHb7 antibody (Middle Region)

Catalog No. ABIN5515618

The Rabbit Polyclonal anti-PCDHb7 antibody has been validated for WB. It is suitable to detect PCDHb7 in samples from Human, Rat and Cow.

Quick Overview for PCDHb7 antibody (Middle Region) (ABIN5515618)

Target: PCDHb7 (Protocadherin beta 7 (PCDHb7))

Reactivity: Human, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHb7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHb7 Antibody

Binding Specificity: Middle Region

Sequence: YAFSYATERI LKTFQINPTS GSLHLKAQLD YEAIQTYTLT IQAKDGGGLS

Predicted Reactivity: Cow: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PCDHB7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PCDHB7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCDHb7

Target: PCDHb7 (Protocadherin beta 7 (PCDHb7))

Alternative Name: PCDHB7

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site.

Alias Symbols: PCDHB7,

Protein Interaction Partner: UBC,

Protein Size: 793

Gene ID: 56129

NCBI Accession: NP_061763

UniProt: Q9Y5E2