ALDOA antibody (C-Term)

Catalog No. ABIN5515767

This Rabbit Polyclonal antibody specifically detects ALDOA in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig and Horse.

Quick Overview for ALDOA antibody (C-Term) (ABIN5515767)

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDOA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ALDOA Antibody

Binding Specificity: C-Term

Sequence: ALQASALKAW GGKKENLKAA QEEYVKRALA NSLACQGKYT PSGQAGAAAS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ALDOA. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ALDOA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Alternative Name: ALDOA

Background: The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Alias Symbols: ALDOA, ALDA,

Protein Interaction Partner: HUWE1, UBC, IFNA4, FUS, ALDOC, ALDOA, SUMO2, SUMO3, MDM2, ADRB2, SUZ12, TNPO3, CS, RAD52, VCPKMT, PIAS4, GALNT6, IQCB1, VCAM1, MLH1, ITGA4, HSP90AB1, HSP90AA1, FN1, ATF2, BCAT2, ALDOB, LIG4, PGK1, LGALS1, HSPD1, AKT1, MYOC, CDK2, CUL2, CUL3, CUL4B, ISG15,

Protein Size: 364

Gene ID: 226

NCBI Accession: NP_908932

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process