CHST8 antibody (N-Term)

Catalog No. ABIN5515899

This Rabbit Polyclonal antibody specifically detects CHST8 in WB. It exhibits reactivity toward Human.

Quick Overview for CHST8 antibody (N-Term) (ABIN5515899)

Target: CHST8 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 8 (CHST8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHST8 Antibody

Binding Specificity: N-Term

Sequence: APQQVPGIKF NIRPRQPHHD LPPGGSQDGD LKEPTERVTR DLSSGAPRGR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N region of human CHST8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST8

Target: CHST8 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 8 (CHST8))

Alternative Name: CHST8

Background: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.

Alias Symbols: PSS3, GalNAc4ST, GALNAC4ST1,

Protein Size: 424

Gene ID: 64377

NCBI Accession: NM_001127895, NP_001121367

UniProt: Q9H2A9