TIAM2 antibody (Middle Region)

Catalog No. ABIN5516179

The Rabbit Polyclonal anti-TIAM2 antibody is suitable to detect TIAM2 in samples from Human. It has been validated for WB.

Quick Overview for TIAM2 antibody (Middle Region) (ABIN5516179)

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TIAM2 Antibody

Binding Specificity: Middle Region

Sequence: NDSQANGMEG PRENQDPPPR SLARHLSDAD RLRKVIQELV DTEKSYVKDL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TIAM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TIAM2

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Alternative Name: TIAM2

Background: This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.

Alias Symbols: STEF, TIAM-2

Protein Size: 167

Gene ID: 26230

NCBI Accession: NM_001010927, NP_001010927

UniProt: Q8IVF5

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha