MBNL2 antibody (N-Term)

Catalog No. ABIN5517157

The Rabbit Polyclonal anti-MBNL2 antibody has been validated for WB. It is suitable to detect MBNL2 in samples from Human.

Quick Overview for MBNL2 antibody (N-Term) (ABIN5517157)

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MBNL2 Antibody

Binding Specificity: N-Term

Sequence: CRQFQRGTCS RSDEECKFAH PPKSCQVENG RVIACFDSLK GRCSRENCKY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MBNL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MBNL2

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Alternative Name: MBNL2

Background: This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.

Alias Symbols: MBLL, MBLL39, PRO2032

Protein Size: 367

Gene ID: 10150

NCBI Accession: NM_001306070, NP_001292999