PLA2G6 antibody (C-Term)

Catalog No. ABIN5517252

This Rabbit Polyclonal antibody specifically detects PLA2G6 in WB. It exhibits reactivity toward Human.

Quick Overview for PLA2G6 antibody (C-Term) (ABIN5517252)

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLA2G6 Antibody

Binding Specificity: C-Term

Sequence: MLTGTLSDRQ PAELHLFRNY DAPETVREPR FNQNVNLRPP AQPSDQLVWR

Characteristics: This is a rabbit polyclonal antibody against PLPL9. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-PLA2G6 antibody is: synthetic peptide directed towards the C-terminal region of Human PLPL9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLA2G6

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Alternative Name: PLA2G6

Background: The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.

Alias Symbols: GVI, PLA2, INAD1, NBIA2, iPLA2, NBIA2A, NBIA2B, PARK14, PNPLA9, CaI-PLA2, IPLA2-VIA, iPLA2beta

Protein Size: 806

Gene ID: 8398

NCBI Accession: XP_006724395

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion