PRPF3 antibody (C-Term)

Catalog No. ABIN5517267

This Rabbit Polyclonal antibody specifically detects PRPF3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Guinea Pig.

Quick Overview for PRPF3 antibody (C-Term) (ABIN5517267)

Target: PRPF3 (PRP3 Pre-mRNA Processing Factor 3 Homolog (PRPF3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRPF3 Antibody

Binding Specificity: C-Term

Sequence: RLMLHRIKWD EQTSNTKGDD DEESDEEAVK KTNKCVLVWE GTAKDRSFGE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRPF3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PRPF3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRPF3

Target: PRPF3 (PRP3 Pre-mRNA Processing Factor 3 Homolog (PRPF3))

Alternative Name: PRPF3

Background: The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.

Alias Symbols: PRPF3, HPRP3, PRP3,

Protein Interaction Partner: FAM9B, TRIM39, SART3, CEP250, AURKB, UBC, TUBG1, LIN28A, MEPCE, WWOX, WBP4, TARDBP, MMS19, FRA10AC1, SNIP1, NKAP, CTNNBL1, ZCCHC10, U2AF2, SF3B2, SLU7, SMNDC1, RBM39, PRPF3, PCBP1, MFAP1, PATL1, RBM25, NOP58, LSM1, PABPC1, PRPF6, NNT, SRRM2, SUPT16H, SF3A

Protein Size: 683

Gene ID: 9129

NCBI Accession: NP_004689

UniProt: O43395