UGT2A1 antibody (Middle Region)

Catalog No. ABIN5517451

The Rabbit Polyclonal anti-UGT2A1 antibody is suitable to detect UGT2A1 in samples from Human. It has been validated for WB.

Quick Overview for UGT2A1 antibody (Middle Region) (ABIN5517451)

Target: UGT2A1 (UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus (UGT2A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details anti-UGT2A1 Antibody

Binding Specificity: Middle Region

Sequence: QIPQKVLWRY KGKKPATLGN NTQLFDWIPQ NDLLGHPKTK AFITHGGTNG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UGT2A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UGT2A1

Target: UGT2A1 (UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus (UGT2A1))

Alternative Name: UGT2A1

Background: The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms.

Alias Symbols: UDPGT2A1

Protein Size: 167

Gene ID: 10941

NCBI Accession: NM_001105677, NP_001099147

UniProt: Q9Y4X1

Pathways: Steroid Hormone Biosynthesis