TXNDC12 antibody (N-Term)

Catalog No. ABIN5517454

The Rabbit Polyclonal anti-TXNDC12 antibody has been validated for WB. It is suitable to detect TXNDC12 in samples from Human.

Quick Overview for TXNDC12 antibody (N-Term) (ABIN5517454)

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TXNDC12 Antibody

Binding Specificity: N-Term

Sequence: METRPRLGAT CLLGFSFLLL VISSDGHNGL GKGFGDHIHW RTLEDGKKEA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TXNDC12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TXNDC12

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Alternative Name: TXNDC12

Background: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.

Alias Symbols: AG1, AGR1, ERP16, ERP18, ERP19, TLP19, hAG-1, PDIA16, hTLP19

Protein Size: 172

Gene ID: 51060

NCBI Accession: NM_015913, NP_056997

UniProt: O95881

Pathways: Cell RedoxHomeostasis