PHC2 antibody (C-Term)

Catalog No. ABIN5517633

This Rabbit Polyclonal antibody specifically detects PHC2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PHC2 antibody (C-Term) (ABIN5517633)

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHC2 Antibody

Binding Specificity: C-Term

Sequence: GMTSGNGNSA SSIAGTAPQN GENKPPQAIV KPQILTHVIE GFVIQEGAEP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PHC2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHC2

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Alternative Name: PHC2

Background: In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PHC2, EDR2, PH2,

Protein Interaction Partner: FAM74A4, FAM74A1, FAM13C, FAM124A, MAGEB6, ZMAT2, ZNF417, MAB21L3, SSX2IP, TRIM41, ZGPAT, L3MBTL3, PCGF5, SPATC1L, FAM161A, ENKD1, KBTBD7, SYT16, THAP7, AEN, CARD9, CBX8, C1orf109, SFMBT1, PRPF31, PPP1R16B, KAT5, PCGF3, RWDD2B, ZBTB24, MORF4L2, RBM39, AP1

Protein Size: 858

Gene ID: 1912

UniProt: Q8IXK0