Dolichol Kinase antibody (N-Term)

Catalog No. ABIN5517789

This Rabbit Polyclonal antibody specifically detects Dolichol Kinase in WB. It exhibits reactivity toward Rat.

Quick Overview for Dolichol Kinase antibody (N-Term) (ABIN5517789)

Target: Dolichol Kinase (DOLK)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dolichol Kinase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dolichol Kinase Antibody

Binding Specificity: N-Term

Sequence: WSLLATLACL VVLYQNAKRS SSESKKHQAP TIARKYFHLI VVATYIPGII

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of rat DOLK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Dolichol Kinase

Target: Dolichol Kinase (DOLK)

Alternative Name: DOLK

Background: The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.

Alias Symbols: DK, DK1, CDG1M, SEC59, TMEM15,

Protein Size: 536

Gene ID: 22845

NCBI Accession: NM_001107826, NP_055723

UniProt: D3ZLM6