C1QL3 antibody (Middle Region)

Catalog No. ABIN5517812

The Rabbit Polyclonal anti-C1QL3 antibody (ABIN5517812) specifically detects C1QL3 in WB. The antibody is reactive with Human samples.

Quick Overview for C1QL3 antibody (Middle Region) (ABIN5517812)

Target: C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C1QL3 Antibody

Binding Specificity: Middle Region

Purpose: C1QL3 Antibody - middle region

Sequence: VPKIAFYAGL KRQHEGYEVL KFDDVVTNLG NHYDPTTGKF TCSIPGIYFF

Characteristics: This is a rabbit polyclonal antibody against C1QL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human C1QL3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68022-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1QL3

Target: C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))

Alternative Name: C1QL3

Background:

Background Information: C1QL3 may regulate the number of excitatory synapses that are formed on hippocampus neurons. It has no effect on inhibitory synapses . It plays a role in glucose homeostasis. Via AMPK signaling pathway, C1QL3 stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, C1QL3 reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production.

Alternative Symbols: C1ql, K100, CTRP13, C1QTNF13

Molecular Weight: 28kDa

Gene ID: 389941

NCBI Accession: NP_001010908

UniProt: Q5VWW1