MNT antibody (C-Term)

Catalog No. ABIN5517930

This Rabbit Polyclonal antibody specifically detects MNT in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Rabbit, Horse, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for MNT antibody (C-Term) (ABIN5517930)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reactivity: Human, Mouse, Cow, Dog, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MNT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MNT Antibody

Binding Specificity: C-Term

Sequence: AAPAQTLVPA PAHLVATAGG GSTVIAHTAT THASVIQTVN HVLQGPGGKH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MNT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Alternative Name: MNT

Background: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Alias Symbols: MNT, BHLHD3, ROX,

Protein Interaction Partner: Dlg4, ELAVL1, CEBPA, MAX, MAD1L1, MYC, HDAC1, SIN3A, MNT, MLX, HMGB1,

Protein Size: 582

Gene ID: 4335

NCBI Accession: NP_064706

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation