DENND3 antibody (C-Term)

Catalog No. ABIN5518005

This Rabbit Polyclonal antibody specifically detects DENND3 in WB. It exhibits reactivity toward Human.

Quick Overview for DENND3 antibody (C-Term) (ABIN5518005)

Target: DENND3 (DENN/MADD Domain Containing 3 (DENND3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DENND3 Antibody

Binding Specificity: C-Term

Sequence: INCMIRVKKQ VWVGSRGLGQ GTPKGKIYVI DAERKTVEKE LVAHMDTVRT

Characteristics: This is a rabbit polyclonal antibody against DENND3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DENND3

Target: DENND3 (DENN/MADD Domain Containing 3 (DENND3))

Alternative Name: DENND3

Background: DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.

Alias Symbols: DENND3, KIAA0870,

Protein Interaction Partner: UBC, YAP1,

Protein Size: 1146

Gene ID: 22898

NCBI Accession: NP_055772