CD3G antibody (C-Term)

Catalog No. ABIN5518078

The Rabbit Polyclonal anti-CD3G antibody has been validated for WB. It is suitable to detect CD3G in samples from Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit and Sheep.

Quick Overview for CD3G antibody (C-Term) (ABIN5518078)

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD3G antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD3G Antibody

Binding Specificity: C-Term

Sequence: ELNAATISGF LFAEIVSIFV LAVGVYFIAG QDGVRQSRAS DKQTLLPNDQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CD3G. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD3G

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD3G

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Alternative Name: CD3G

Background: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Alias Symbols: T3G

Protein Interaction Partner: UBC, NR3C1, FYN, CD3E, CD3D,

Protein Size: 182

Gene ID: 917

NCBI Accession: XP_006719004

UniProt: P09693

Pathways: TCR Signaling, CXCR4-mediated Signaling Events